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Last updated: 2017/5/28
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CES1 polyclonal antibody

  • Catalog # : PAB7531
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CES1.
  • Immunogen:
  • A synthetic peptide corresponding to human CES1.
  • Sequence:
  • C-NTQAAQKLKDKE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 62.6, 62.5, 62.4
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all three reported isoforms (NP_001020366.1; NP_001020365.1; NP_001257.4).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:8000)
    Western blot (0.03-0.1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CES1 polyclonal antibody (Cat # PAB7531) (0.03 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • CES1 polyclonal antibody (Cat # PAB7531) (2.5 ug/mL) staining of paraffin embedded human lung. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1066
  • Protein Accession#:
  • NP_001020366.1;NP_001020365.1;NP_001257.4
  • Gene Name:
  • CES1
  • Gene Alias:
  • ACAT,CEH,CES2,HMSE,HMSE1,MGC117365,PCE-1,SES1,TGH
  • Gene Description:
  • carboxylesterase 1 (monocyte/macrophage serine esterase 1)
  • Gene Summary:
  • Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • acyl coenzyme A:cholesterol acyltransferase,carboxylesterase 1,carboxylesterase 2 (liver),cholesteryl ester hydrolase,egasyn,liver carboxylesterase,triacylglycerol hydrolase
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