TBC1D10C polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TBC1D10C.
Immunogen
A synthetic peptide corresponding to human TBC1D10C.
Sequence
C-PRRKPQTRGKTFH
Host
Goat
Theoretical MW (kDa)
49.7
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TBC1D10C
Entrez GeneID
374403Protein Accession#
NP_940919.1Gene Name
TBC1D10C
Gene Alias
CARABIN, FLJ00332, MGC46488
Gene Description
TBC1 domain family, member 10C
Omim ID
610831Gene Ontology
HyperlinkGene Summary
Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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Publication Reference
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Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin.
Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO.
Nature 2007 Jan; 445(7126):433.
Application：IP, WB, Human, Jurkat cells.
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Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin.
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