ARSA polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
ARSA polyclonal antibody (Cat # PAB7518) (0.5 ug/mL) staining of mouse testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ARSA.
Immunogen
A synthetic peptide corresponding to internal region of human ARSA.
Sequence
C-YDLSKDPGENYN
Host
Goat
Theoretical MW (kDa)
53.6
Reactivity
Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ARSA polyclonal antibody (Cat # PAB7518) (0.5 ug/mL) staining of mouse testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ARSA
Entrez GeneID
410Protein Accession#
NP_000478.2Gene Name
ARSA
Gene Alias
MLD
Gene Description
arylsulfatase A
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000196546|OTTHUMP00000196548
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Interactome
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Pathway
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Disease
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Publication Reference
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Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy.
Sevin C, Benraiss A, Van Dam D, Bonnin D, Nagels G, Verot L, Laurendeau I, Vidaud M, Gieselmann V, Vanier M, De Deyn PP, Aubourg P, Cartier N.
Human Molecular Genetics 2006 Jan; 15(1):53.
Application：ELISA, IF, IHC, Mouse, 293T cells, Brain.
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Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy.
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