ADORA1 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of ADORA1.
Immunogen
A synthetic peptide corresponding to human ADORA1.
Sequence
NDHFRCQPAPPIDED
Host
Goat
Theoretical MW (kDa)
36.5
Specificity
Both reported isoforms represent identical protein (NP_000665.1; NP_001041695.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADORA1
Entrez GeneID
134Protein Accession#
NP_000665.1;NP_001041695.1Gene Name
ADORA1
Gene Alias
RDC7
Gene Description
adenosine A1 receptor
Omim ID
102775Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000039090|OTTHUMP00000039091
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function.
Funakoshi H, Chan TO, Good JC, Libonati JR, Piuhola J, Chen X, MacDonnell SM, Lee LL, Herrmann DE, Zhang J, Martini J, Palmer TM, Sanbe A, Robbins J, Houser SR, Koch WJ, Feldman AM.
Circulation 2006 Nov; 114(21):2240.
Application:WB-Ti, Mouse , Mouse hearts.
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Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function.
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