BDKRB1 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of BDKRB1.
Immunogen
A synthetic peptide corresponding to human BDKRB1.
Sequence
KVWELYKQCTPK
Host
Goat
Theoretical MW (kDa)
40.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
BDKRB1 polyclonal antibody (Cat # PAB7493) (2 ug/mL) staining of K-562 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — BDKRB1
Entrez GeneID
623Protein Accession#
NP_000701.2Gene Name
BDKRB1
Gene Alias
B1BKR, B1R, BKB1R, BKR1, BRADYB1
Gene Description
bradykinin receptor B1
Omim ID
600337Gene Ontology
HyperlinkGene Summary
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq
Other Designations
BK-1 receptor|bradykinin B1 receptor|bradykinin receptor 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Double-stranded RNA increases kinin B1 receptor expression and function in human airway epithelial cells.
Bengtson SH, Eddleston J, Christiansen SC, Zuraw BL.
International Immunopharmacology 2007 Dec; 7(14):1880.
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Double-stranded RNA increases kinin B1 receptor expression and function in human airway epithelial cells.
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