SERPINF2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
SERPINF2 polyclonal antibody (Cat # PAB7490) (0.1 ug/mL) staining of human duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
SERPINF2 polyclonal antibody (Cat # PAB7490, 3.8 ug/mL) staining of paraffin embedded human liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SERPINF2.
Immunogen
A synthetic peptide corresponding to human SERPINF2.
Sequence
C-KDFLQSLKGFPRGDK
Host
Goat
Theoretical MW (kDa)
54.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
SERPINF2 polyclonal antibody (Cat # PAB7490) (0.1 ug/mL) staining of human duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
SERPINF2 polyclonal antibody (Cat # PAB7490, 3.8 ug/mL) staining of paraffin embedded human liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SERPINF2
Entrez GeneID
5345Protein Accession#
NP_000925.2Gene Name
SERPINF2
Gene Alias
A2AP, AAP, ALPHA-2-PI, API, PLI
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Omim ID
262850Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Alpha2-antiplasmin plays a significant role in acute pulmonary embolism.
Matsuno H, Okada K, Ueshima S, Matsuo O, Kozawa O.
Journal of Thrombosis and Haemostasis 2003 Aug; 1(8):1734.
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Alpha2-antiplasmin plays a significant role in acute pulmonary embolism.
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