Irak3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The Irak3 polyclonal antibody (Cat # PAB7483) (0.05 ug/mL) staining of rat liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detceted with chemiluminescence.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of Irak3.
Immunogen
A synthetic peptide corresponding to mouse Irak3.
Sequence
C-GHSYGSKPMEKR
Host
Goat
Theoretical MW (kDa)
67.8
Reactivity
Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Western Blot (0.05-0.2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
The Irak3 polyclonal antibody (Cat # PAB7483) (0.05 ug/mL) staining of rat liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detceted with chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — Irak3
Entrez GeneID
73914Protein Accession#
NP_082955.2Gene Name
Irak3
Gene Alias
4833428C18Rik, AI563835, IRAK-M
Gene Description
interleukin-1 receptor-associated kinase 3
Gene Ontology
HyperlinkOther Designations
-
-
Publication Reference
-
TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.
Zhang CJ, Jiang M, Zhou H, Liu W, Wang C, Kang Z, Han B, Zhang Q, Chen X, Xiao J, Fisher A, Kaiser WJ, Murayama MA, Iwakura Y, Gao J, Carman J, Dongre A, Dubyak G, Abbott DW, Shi FD, Ransohoff RM, Li X.
The Journal of Clinical Investigation 2018 Dec; 128(12):5399.
Application：IP, WB, Mouse, Mouse primary microglia.
-
IRAK-M is involved in the pathogenesis of early-onset persistent asthma.
Balaci L, Spada MC, Olla N, Sole G, Loddo L, Anedda F, Naitza S, Zuncheddu MA, Maschio A, Altea D, Uda M, Pilia S, Sanna S, Masala M, Crisponi L, Fattori M, Devoto M, Doratiotto S, Rassu S, Mereu S, Giua E, Cadeddu NG, Atzeni R, Pelosi U, Corrias A, Perra R, Torrazza PL, Pirina P, Ginesu F, Marcias S, Schintu MG, Del Giacco GS, Manconi PE, Malerba G, Bisognin A, Trabetti E, Boner A, Pescollderungg L, Pignatti PF, Schlessinger D, Cao A, Pilia G.
American Journal of Human Genetics 2007 Jun; 80(6):1103.
Application：IHC-P, Human, Human lung biopsy.
-
TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com