CHRNB3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CHRNB3.
Immunogen
A synthetic peptide corresponding to human CHRNB3.
Sequence
C-SRHVKKEHFISQ
Host
Goat
Theoretical MW (kDa)
52.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CHRNB3 polyclonal antibody (Cat # PAB7469) (1 ug/mL) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CHRNB3
Entrez GeneID
1142Protein Accession#
NP_000740.1Gene Name
CHRNB3
Gene Alias
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Gene Description
cholinergic receptor, nicotinic, beta 3
Omim ID
118508Gene Ontology
HyperlinkGene Summary
nicotinic
Other Designations
acetylcholine receptor, neuronal nicotinic, beta-3 subunit|cholinergic receptor, nicotinic, beta polypeptide 3
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Interactome
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Disease
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Publication Reference
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The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco.
Zeiger JS, Haberstick BC, Schlaepfer I, Collins AC, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Lessem J, McQueen MB, Rhee SH, Ehringer MA.
Human Molecular Genetics 2008 Mar; 17(5):724.
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The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco.
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