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Last updated: 2017/11/19
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DUOX1 polyclonal antibody

  • Catalog # : PAB7468
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of DUOX1.
  • Immunogen:
  • A synthetic peptide corresponding to human DUOX1.
  • Sequence:
  • EKFQRSCLHQTVQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 177
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_059130.2 , NP_787954.1) which are identical.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • DUOX1 polyclonal antibody (Cat # PAB7468) (4 ug/mL) staining of paraffin embedded human thyroid gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_059130.2;NP_787954.1
  • Gene Name:
  • DUOX1
  • Gene Alias:
  • LNOX1,MGC138840,MGC138841,NOXEF1,THOX1
  • Gene Description:
  • dual oxidase 1
  • Gene Summary:
  • The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq
  • Other Designations:
  • NADPH thyroid oxidase 1,flavoprotein NADPH oxidase,nicotinamide adenine dinucleotide phosphate oxidase
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