IGFBP4 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of IGFBP4.
Immunogen
A synthetic peptide corresponding to human IGFBP4.
Sequence
KGELDCHQLADSFRE
Host
Goat
Theoretical MW (kDa)
27.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
IGFBP4 polyclonal antibody (Cat # PAB7464) (1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IGFBP4
Entrez GeneID
3487Protein Accession#
NP_001543.2Gene Name
IGFBP4
Gene Alias
BP-4, HT29-IGFBP, IBP4, IGFBP-4
Gene Description
insulin-like growth factor binding protein 4
Omim ID
146733Gene Ontology
HyperlinkGene Summary
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq
Other Designations
IGF-binding protein 4|insulin-like growth factor-binding protein 4
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Interactome
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Disease
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Publication Reference
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Biology of insulin-like growth factor binding protein-4 and its role in cancer (review).
Durai R, Davies M, Yang W, Yang SY, Seifalian A, Goldspink G, Winslet M.
International Journal of Oncology 2006 Jun; 28(6):1317.
Application:WB-Ce, WB-Tr, Human, Mouse, ALVA-31 cells, Cancers, M12 cells.
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Biology of insulin-like growth factor binding protein-4 and its role in cancer (review).
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