LYN polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of LYN.
Immunogen
A synthetic peptide corresponding to human LYN.
Sequence
C-KTQPVRNTERT
Host
Goat
Theoretical MW (kDa)
58.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
LYN polyclonal antibody (Cat # PAB7459) (0.1 ug/mL) staining of U-937 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — LYN
Entrez GeneID
4067Protein Accession#
NP_002341.1Gene Name
LYN
Gene Alias
FLJ26625, JTK8
Gene Description
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Omim ID
165120Gene Ontology
HyperlinkOther Designations
Yamaguchi sarcoma viral (v-yes-1) oncogene homolog|Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog
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Interactome
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Pathway
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Disease
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Publication Reference
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Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.
Okamoto M, Hayakawa F, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T.
Leukemia 2007 Mar; 21(3):403.
Application:IP, WB, Mouse, 32D cells.
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Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.
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