FZD7 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
FZD7 polyclonal antibody (Cat # PAB7449) (0.3 ug/mL) staining of HepG2 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FZD7.
Immunogen
A synthetic peptide corresponding to human FZD7.
Sequence
C-RFYHRLSHSSKGET
Host
Goat
Theoretical MW (kDa)
63.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
FZD7 polyclonal antibody (Cat # PAB7449) (0.3 ug/mL) staining of HepG2 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FZD7
Entrez GeneID
8324Protein Accession#
NP_0.03498.1Gene Name
FZD7
Gene Alias
FzE3
Gene Description
frizzled homolog 7 (Drosophila)
Omim ID
603410Gene Ontology
HyperlinkGene Summary
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq
Other Designations
Frizzled, drosophila, homolog of, 7|frizzled 7
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Interactome
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Pathway
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Disease
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Publication Reference
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Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids.
Vincan E, Darcy PK, Farrelly CA, Faux MC, Brabletz T, Ramsay RG.
Oncogene 2007 Apr; 26(16):2340.
Application：IHC-P, Human, Human colorectal carcinomas.
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Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids.
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