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Last updated: 2016/11/27
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PC polyclonal antibody

  • Catalog # : PAB7443
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PC.
  • Immunogen:
  • A synthetic peptide corresponding to human PC.
  • Sequence:
  • C-KFKEVKKAYVEANQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 130
  • Reactivity:
  • Mouse
  • Specificity:
  • All reported variants (NP_000911.2, NP_0010.35806.1, NP_071504.2) represent identical protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.03-0.1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • PC polyclonal antibody (Cat # PAB7443) (0.03 ug/mL) staining of mouse liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • 293 overexpressing Human PC and probed with PC polyclonal antibody (Cat # PAB7443) (mock transfection in first lane), tested by Origene.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5091
  • Protein Accession#:
  • NP_000911.2;NP_0010.35806.1;NP_071504.2
  • Gene Name:
  • PC
  • Gene Alias:
  • PCB
  • Gene Description:
  • pyruvate carboxylase
  • Gene Summary:
  • This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq
  • Other Designations:
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