PITX3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
PITX3 polyclonal antibody (Cat # PAB7438) (1 ug/mL) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PITX3.
Immunogen
A synthetic peptide corresponding to human PITX3.
Sequence
PEHGCKGQEHSD
Host
Goat
Theoretical MW (kDa)
31.8
Reactivity
Human
Specificity
This antibody is not excpected to cross-react with PITX1 and PITX2.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PITX3 polyclonal antibody (Cat # PAB7438) (1 ug/mL) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PITX3
Entrez GeneID
5309Protein Accession#
NP_005020.1Gene Name
PITX3
Gene Alias
CTPP4, MGC12766, PTX3
Gene Description
paired-like homeodomain 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq
Other Designations
OTTHUMP00000020362|homeobox protein PITX3
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Interactome
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Disease
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Publication Reference
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A MicroRNA feedback circuit in midbrain dopamine neurons.
Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, Murchison E, Hannon G, Abeliovich A.
Science 2007 Aug; 317(5842):1220.
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A MicroRNA feedback circuit in midbrain dopamine neurons.
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