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Last updated: 2017/12/10
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PTPRM polyclonal antibody

  • Catalog # : PAB7422
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PTPRM.
  • Immunogen:
  • A synthetic peptide corresponding to human PTPRM.
  • Sequence:
  • C-KLIRQVDKWQEEYN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 165, 164
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_001098714.1 and NP_002836.3).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5797
  • Protein Accession#:
  • NP_001098714.1;NP_002836.3
  • Gene Name:
  • PTPRM
  • Gene Alias:
  • MGC166994,PTPRL1,R-PTP-MU,RPTPM,RPTPU,hR-PTPu
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, M
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • protein tyrosine phosphatase mu,protein tyrosine phosphatase, receptor type, mu polypeptide
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