P2RY1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of P2RY1.
Immunogen
A synthetic peptide corresponding to amino acids 247-257 of human P2RY1.
Sequence
C-KDLDNSPLRRK
Host
Goat
Theoretical MW (kDa)
42.1
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — P2RY1
Entrez GeneID
5028Protein Accession#
NP_002554.1Gene Name
P2RY1
Gene Alias
P2Y1
Gene Description
purinergic receptor P2Y, G-protein coupled, 1
Omim ID
601167Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq
Other Designations
ATP receptor|P2 purinoceptor subtype Y1|P2Y purinoceptor 1|platelet ADP receptor|purinergic receptor P2Y1
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Interactome
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Pathway
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Disease
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Publication Reference
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Calmodulin interacts with the platelet ADP receptor P2Y1.
Arthur JF, Shen Y, Mu FT, Leon C, Gachet C, Berndt MC, Andrews RK.
Biochemical Journal 2006 Sep; 398(3):339.
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Calmodulin interacts with the platelet ADP receptor P2Y1.
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