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CYTH2 polyclonal antibody

  • Catalog # : PAB7405
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CYTH2.
  • Immunogen:
  • A synthetic peptide corresponding to human CYTH2.
  • Sequence:
  • EDGVYEPPDLTP-C
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 46.5, 46.5
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_004219.2, NP_059431.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.5-1.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CYTH2 polyclonal antibody (Cat # PAB7405) (0.5 ug/mL) staining of human brain (cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9266
  • Protein Accession#:
  • NP_004219.2;NP_059431.1
  • Gene Name:
  • CYTH2
  • Gene Alias:
  • ARNO,CTS18,CTS18.1,PSCD2,PSCD2L,SEC7L,Sec7p-L,Sec7p-like
  • Gene Description:
  • cytohesin 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • ARF exchange factor,ARF nucleotide-binding site opener,pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2),pleckstrin homology, Sec7 and coiled-coil domains 2-like,pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2)
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