COL4A3BP polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
COL4A3BP polyclonal antibody (Cat # PAB7393) (0.5 ug/mL) staining of Mouse Heart lysate (1) + peptide (2) (35 ug protein in RIPA buffer). Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of COL4A3BP.
Immunogen
A synthetic peptide corresponding to human COL4A3BP.
Sequence
DHDSAPLNNRC
Host
Goat
Theoretical MW (kDa)
70.8, 60
Reactivity
Mouse
Specificity
This antibody is expected to recognize both reported isoforms (NP_005704.1 and NP_112729.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
COL4A3BP polyclonal antibody (Cat # PAB7393) (0.5 ug/mL) staining of Mouse Heart lysate (1) + peptide (2) (35 ug protein in RIPA buffer). Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — COL4A3BP
Entrez GeneID
10087Protein Accession#
NP_005704.1;NP_112729.1Gene Name
COL4A3BP
Gene Alias
CERT, CERTL, FLJ20597, GPBP, STARD11
Gene Description
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Omim ID
604677Gene Ontology
HyperlinkGene Summary
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Goodpasture antigen-binding protein|OTTHUMP00000128248|OTTHUMP00000128249|START domain containing 11|StAR-related lipid transfer (START) domain containing 11|alpha 3 type IV collagen binding protein|ceramide transporter|lipid-transfer protein CERTL
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Interactome
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Publication Reference
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Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.
Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B.
Cancer Cell 2007 Jun; 11(6):498.
Application：WB-Ce, Human, A-549, ADR, HCT-116, MCF-7, MDA, SKOV3, TR cells.
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Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.
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