STS polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of STS.
Immunogen
A synthetic peptide corresponding to human STS.
Sequence
C-QAGQKIDEPTSN
Host
Goat
Theoretical MW (kDa)
65.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
STS polyclonal antibody (Cat # PAB7370) (0.01 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — STS
Entrez GeneID
412Protein Accession#
NP_000342.2Gene Name
STS
Gene Alias
ARSC, ARSC1, ASC, ES, SSDD
Gene Description
steroid sulfatase (microsomal), isozyme S
Omim ID
308100Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq
Other Designations
OTTHUMP00000022868|arylsulfatase C|estrone sulfatase|steryl-sulfatase|steryl-sulfate sulfohydrolase
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Interactome
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Pathway
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Disease
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Publication Reference
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A role for sulfation-desulfation in the uptake of bisphenol a into breast tumor cells.
Stowell CL, Barvian KK, Young PC, Bigsby RM, Verdugo DE, Bertozzi CR, Widlanski TS.
Chemistry & Biology 2006 Aug; 13(8):891.
Application:Func, Human, MCF-7 cells.
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A role for sulfation-desulfation in the uptake of bisphenol a into breast tumor cells.
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