KCNJ6 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
KCNJ6 polyclonal antibody (Cat # PAB7366) (1 ug/mL) staining of human brain (substantia nigra) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of KCNJ6.
Immunogen
A synthetic peptide corresponding to human KCNJ6.
Sequence
C-SSKLNQHAELET
Host
Goat
Theoretical MW (kDa)
48.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
KCNJ6 polyclonal antibody (Cat # PAB7366) (1 ug/mL) staining of human brain (substantia nigra) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KCNJ6
Entrez GeneID
3763Protein Accession#
NP_002231.1Gene Name
KCNJ6
Gene Alias
BIR1, GIRK2, KATP2, KCNJ7, KIR3.2, MGC126596, hiGIRK2
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 6
Omim ID
600877Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq
Other Designations
G protein-activated inward rectifier potassium channel 2|OTTHUMP00000109101|inward rectifier potassium channel KIR3.2|potassium inwardly-rectifying channel J6
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Interactome
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Disease
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Publication Reference
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XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization.
Lu M, Lin SC, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H.
Molecular Cell 2007 Jun; 26(5):689.
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XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization.
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