VTCN1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of VTCN1.
Immunogen
A synthetic peptide corresponding to internal region of human VTCN1.
Sequence
C-SKGKGNANLEYK
Host
Goat
Theoretical MW (kDa)
30.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
VTCN1 polyclonal antibody (Cat # PAB7331) (0.5 ug/mL) staining of human pancrease lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — VTCN1
Entrez GeneID
79679Protein Accession#
NP_078902.2Gene Name
VTCN1
Gene Alias
B7-H4, B7H4, B7S1, B7X, B7h.5, FLJ22418, PRO1291, RP11-229A19.4, VCTN1
Gene Description
V-set domain containing T cell activation inhibitor 1
Omim ID
608162Gene Ontology
HyperlinkGene Summary
B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (e.g., CD28; MIM 186760) on T lymphocytes.[supplied by OMIM
Other Designations
OTTHUMP00000013947|T cell costimulatory molecule B7x|immune costimulatory protein B7-H4
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Interactome
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Disease
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Publication Reference
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B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival.
Krambeck AE, Thompson RH, Dong H, Lohse CM, Park ES, Kuntz SM, Leibovich BC, Blute ML, Cheville JC, Kwon ED.
PNAS 2006 Jul; 103(27):10391.
Application:IHC-Fr, Human, Human renal cell carcinoma.
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B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival.
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