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Last updated: 2017/10/15

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PDE11A polyclonal antibody

  • Catalog # : PAB7327
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PDE11A.
  • Immunogen:
  • A synthetic peptide corresponding to human PDE11A.
  • Sequence:
  • C-NSFKESMEKSSYSD
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 105, 78.1, 65.7, 55.
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all four reported isoforms (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:2000)
    Western Blot (0.5-1.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • PDE11A polyclonal antibody (Cat # PAB7327) (1 ug/mL) staining of human prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_058649.3;NP_001070665.1;NP_001070826.1;NP_001070664.1
  • Gene Name:
  • PDE11A
  • Gene Alias:
  • FLJ23693,MGC133355,MGC133356,PPNAD2
  • Gene Description:
  • phosphodiesterase 11A
  • Gene Summary:
  • The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cAMP and cGMP cyclic nucleotide phosphodiesterase 11A,cyclic nucleotide phosphodiesterase 11A,dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
  • Gene Pathway
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