AIP polyclonal antibody
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More Files
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Western Blot (Cell lysate)
AIP polyclonal antibody (Cat # PAB7275) (0.02 ug/mL) staining of NIH/3T3 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot (Transfected lysate)
293 overexpressing AIP and probed with AIP polyclonal antibody (Cat # PAB7275) (mock transfection in first lane), tested by Origene.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of AIP.
Immunogen
A synthetic peptide corresponding to human AIP.
Sequence
C-EARIRQKDEEDKAR
Host
Goat
Theoretical MW (kDa)
37.7
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Western Blot (0.02-0.06 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
AIP polyclonal antibody (Cat # PAB7275) (0.02 ug/mL) staining of NIH/3T3 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Western Blot (Transfected lysate)
293 overexpressing AIP and probed with AIP polyclonal antibody (Cat # PAB7275) (mock transfection in first lane), tested by Origene.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AIP
Entrez GeneID
9049Protein Accession#
NP_003968.1Gene Name
AIP
Gene Alias
ARA9, FKBP16, FKBP37, SMTPHN, XAP2
Gene Description
aryl hydrocarbon receptor interacting protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. [provided by RefSeq
Other Designations
HBV-X associated protein|aryl hydrocarbon receptor-interacting protein
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Interactome
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Disease
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Publication Reference
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Pituitary adenoma predisposition caused by germline mutations in the AIP gene.
Vierimaa O, Georgitsi M, Lehtonen R, Vahteristo P, Kokko A, Raitila A, Tuppurainen K, Ebeling TM, Salmela PI, Paschke R, Gündogdu S, De Menis E, Mäkinen MJ, Launonen V, Karhu A, Aaltonen LA.
Science 2006 May; 312(5777):1228.
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Pituitary adenoma predisposition caused by germline mutations in the AIP gene.
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