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Last updated: 2017/12/10
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TIA1 polyclonal antibody

  • Catalog # : PAB7257
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TIA1.
  • Immunogen:
  • A synthetic peptide corresponding to human TIA1.
  • Sequence:
  • C-PKSTYESNTKQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 41.8, 43
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_071320.1 and NP_071505.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • TIA1 polyclonal antibody (Cat # PAB7257) (0.1 ug/mL) staining of Jurkat cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7072
  • Protein Accession#:
  • NP_071320.1;NP_071505.1
  • Gene Name:
  • TIA1
  • Gene Alias:
  • -
  • Gene Description:
  • TIA1 cytotoxic granule-associated RNA binding protein
  • Gene Summary:
  • The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq
  • Other Designations:
  • T-cell-restricted intracellular antigen-1,TIA1 cytotoxic granule-associated RNA-binding protein,TIA1 protein,cytotoxic granule-associated RNA-binding protein,nucleolysin TIA-1 isoform p40,p40-TIA-1 (containing p15-TIA-1)
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