KLK5 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
KLK5 polyclonal antibody (Cat # PAB7227) (0.1 ug/mL) staining of human prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of KLK5.
Immunogen
A synthetic peptide corresponding to human KLK5.
Sequence
KAGRDSCQGD
Host
Goat
Theoretical MW (kDa)
32
Reactivity
Human
Specificity
All variants (NP_0.36559.1, NP_001070959.1, NP_001070960.1) represent identical protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
KLK5 polyclonal antibody (Cat # PAB7227) (0.1 ug/mL) staining of human prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KLK5
Entrez GeneID
25818Protein Accession#
NP_0.36559.1;NP_001070959.1;NP_001070960.1Gene Name
KLK5
Gene Alias
KLK-L2, KLKL2, SCTE
Gene Description
kallikrein-related peptidase 5
Omim ID
605643Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
kallikrein 5|kallikrein-like protein 2|stratum corneum tryptic enzyme
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Interactome
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Disease
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Publication Reference
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Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression.
Michael IP, Pampalakis G, Mikolajczyk SD, Malm J, Sotiropoulou G, Diamandis EP.
The Journal of Biological Chemistry 2006 May; 281(18):12743.
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Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression.
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