VANGL2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of VANGL2.
Immunogen
A synthetic peptide corresponding to human VANGL2.
Sequence
C-QKYLRTTKQQPYH
Host
Goat
Theoretical MW (kDa)
59.7
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
VANGL2 polyclonal antibody (Cat # PAB7207) (0.3 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — VANGL2
Entrez GeneID
57216Protein Accession#
NP_065068.1Gene Name
VANGL2
Gene Alias
KIAA1215, LPP1, LTAP, MGC119403, MGC119404, STB1, STBM, STBM1
Gene Description
vang-like 2 (van gogh, Drosophila)
Omim ID
600533Gene Ontology
HyperlinkGene Summary
The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway (Kibar et al., 2001 [PubMed 11431695]).[supplied by OMIM
Other Designations
OTTHUMP00000031861|loop-tail-associated protein|strabismus|vang, van gogh-like 2|vang-like 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.
Kibar Z, Vogan KJ, Groulx N, Justice MJ, Underhill DA, Gros P.
Nature Genetics 2001 Jul; 28(3):251.
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Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.
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