UBASH3A polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of UBASH3A.
Immunogen
A synthetic peptide corresponding to human UBASH3A.
Sequence
QQCSTPDGKYYRPD
Host
Goat
Theoretical MW (kDa)
74.1, 69.8
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_061834.1 and NP_001001895.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
UBASH3A polyclonal antibody (Cat # PAB7193) (2.5 ug/mL) staining of paraffin embedded human spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — UBASH3A
Entrez GeneID
53347Protein Accession#
NP_061834.1;NP_001001895.1Gene Name
UBASH3A
Gene Alias
CLIP4, STS-2, TULA
Gene Description
ubiquitin associated and SH3 domain containing, A
Omim ID
605736Gene Ontology
HyperlinkGene Summary
O
Other Designations
T-cell ubiquitin ligand protein
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Interactome
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Disease
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Publication Reference
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Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases.
Kowanetz K, Crosetto N, Haglund K, Schmidt MH, Heldin CH, Dikic I.
The Journal of Biological Chemistry 2004 Jul; 279(31):32786.
Application:WB, Human, Mouse, CHO, HEK 293T cells.
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Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases.
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