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Last updated: 2016/12/11
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APPL1 polyclonal antibody

  • Catalog # : PAB7191
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of APPL1.
  • Immunogen:
  • A synthetic peptide corresponding to human APPL1.
  • Sequence:
  • C-NRYSRLSKKRENDK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 79.7
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • APPL1 polyclonal antibody (Cat # PAB7191) (0.5 ug/mL) staining of A) rat aortic smooth muscle cell lysate B) after infection with human APPL1 adenovirus for 48hrs. Detected by chemiluminescence. Data kindly provided by Dr. L. Jia, Ann Arbor, USA.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • APPL1
  • Gene Alias:
  • APPL,DIP13alpha
  • Gene Description:
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • Gene Summary:
  • The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq
  • Other Designations:
  • AKT2 interactor,adaptor protein containing pH domain, PTB domain and leucine zipper motif 1,signaling adaptor protein DIP13alpha
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