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Last updated: 2016/12/4
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HNF1B polyclonal antibody

  • Catalog # : PAB7189
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HNF1B.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human HNF1B.
  • Sequence:
  • C-QAYDRQKNPSKEER
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 61.3
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_000449.1; NP_001159395.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HNF1B polyclonal antibody (Cat # PAB7189) (0.1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunocytochemistry
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunocytochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6928
  • Protein Accession#:
  • NP_000449.1;NP_006472.1
  • Gene Name:
  • HNF1B
  • Gene Alias:
  • FJHN,HNF1beta,HNF2,HPC11,LF-B3,LFB3,MODY5,TCF2,VHNF1
  • Gene Description:
  • HNF1 homeobox B
  • Gene Summary:
  • This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene
  • Other Designations:
  • transcription factor 2,transcription factor 2, hepatic,transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor
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