AOC3 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of AOC3.
Immunogen
A synthetic peptide corresponding to human AOC3.
Sequence
C-DEDPSFYSADSIY
Host
Goat
Theoretical MW (kDa)
84.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
AOC3 polyclonal antibody (Cat # PAB7185, 3.8 ug/mL) staining of paraffin embedded human liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AOC3
Entrez GeneID
8639Protein Accession#
NP_003725.1Gene Name
AOC3
Gene Alias
HPAO, SSAO, VAP-1, VAP1
Gene Description
amine oxidase, copper containing 3 (vascular adhesion protein 1)
Omim ID
603735Gene Ontology
HyperlinkGene Summary
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream. [provided by RefSeq
Other Designations
amine oxidase, copper containing 3|copper amine oxidase|semicarbazide-sensitive amine oxidase|vascular adhesion protein 1
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Interactome
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Pathway
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Publication Reference
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Loss of vascular adhesion protein-1 expression in intratumoral microvessels of human skin melanoma.
Forster-Horvath C, Dome B, Paku S, Ladanyi A, Somlai B, Jalkanen S, Timar J.
Melanoma Research 2004 Apr; 14(2):135.
Application:IEM, IF, IHC-Fr, Human, Human skin melanoma.
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Loss of vascular adhesion protein-1 expression in intratumoral microvessels of human skin melanoma.
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