FADS1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FADS1.
Immunogen
A synthetic peptide corresponding to human FADS1.
Sequence
C-QPSFEPTKNKELTDE
Host
Goat
Theoretical MW (kDa)
51.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FADS1 polyclonal antibody (Cat # PAB7176) (0.3 ug/mL) staining of human lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FADS1
Entrez GeneID
3992Protein Accession#
NP_0.37534.2Gene Name
FADS1
Gene Alias
D5D, FADS6, FADSD5, FLJ38956, FLJ90273, LLCDL1, TU12
Gene Description
fatty acid desaturase 1
Omim ID
606148Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq
Other Designations
delta(5) desaturase|delta-5 desaturase|delta-5 fatty acid desaturase|linoleoyl-CoA desaturase (delta-6-desaturase)-like 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Cloning, expression, and fatty acid regulation of the human delta-5 desaturase.
Cho HP, Nakamura M, Clarke SD.
The Journal of Biological Chemistry 1999 Dec; 274(52):37335.
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Cloning, expression, and fatty acid regulation of the human delta-5 desaturase.
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