GNRHR polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
GNRHR polyclonal antibody (Cat # PAB7168) (0.5 ug/mL) staining of human peripheral blood mononucleocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GNRHR.
Immunogen
A synthetic peptide corresponding to human GNRHR.
Sequence
C-QKWTQKKEKGK
Host
Goat
Theoretical MW (kDa)
37.7, 27.7
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_00.0397.1, NP_001012781.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
GNRHR polyclonal antibody (Cat # PAB7168) (0.5 ug/mL) staining of human peripheral blood mononucleocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — GNRHR
Entrez GeneID
2798Protein Accession#
NP_00.0397.1;NP_001012781.1Gene Name
GNRHR
Gene Alias
GNRHR1, GRHR, LHRHR, LRHR
Gene Description
gonadotropin-releasing hormone receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq
Other Designations
gonadotropin-releasing hormone (type 1) receptor 1|leutinizing hormone releasing horomone receptor|leutinizing-releasing hormone receptor|luliberin receptor|type I GnRH receptor
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells.
Yeung CM, An BS, Cheng CK, Chow BK, Leung PC.
Molecular Human Reproduction 2005 Nov; 11(11):837.
-
Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com