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Last updated: 2016/12/4
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CNTFR polyclonal antibody

  • Catalog # : PAB7167
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CNTFR.
  • Immunogen:
  • A synthetic peptide corresponding to human CNTFR.
  • Sequence:
  • CRSNTYPKGFY
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 40.6
  • Reactivity:
  • Mouse
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_671693.1, NP_001833.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CNTFR polyclonal antibody (Cat # PAB7167) (0.3 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1271
  • Protein Accession#:
  • NP_671693.1;NP_001833.1
  • Gene Name:
  • CNTFR
  • Gene Alias:
  • MGC1774
  • Gene Description:
  • ciliary neurotrophic factor receptor
  • Gene Summary:
  • This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq
  • Other Designations:
  • CNTFR alpha,OTTHUMP00000021270,OTTHUMP00000021271,ciliary neurotrophic factor receptor alpha
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