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Last updated: 2016/12/4
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HAP1 polyclonal antibody

  • Catalog # : PAB7160
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HAP1.
  • Immunogen:
  • A synthetic peptide corresponding to human HAP1.
  • Sequence:
  • C-RYDFRYSEDREQ
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 75.5, 69.6
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all reported isoforms (NP_0.03940.1, NP_817084.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HAP1 polyclonal antibody (Cat # PAB7160) (0.1 ug/mL) staining of human brain (hippocampus) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9001
  • Protein Accession#:
  • NP_0.03940.2;NP_817084.1
  • Gene Name:
  • HAP1
  • Gene Alias:
  • HAP2,HIP5,HLP,hHLP1
  • Gene Description:
  • huntingtin-associated protein 1
  • Gene Summary:
  • Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000164747,huntingtin-associated protein 2,neuroan 1
  • Gene Pathway
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