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Last updated: 2017/12/10
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FOXP2 polyclonal antibody

  • Catalog # : PAB7158
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of FOXP2.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human FOXP2.
  • Sequence:
  • C-DEVEYQKRRSQKIT
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 82.6
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is expected to recognize isoform I (NP_055306.1), isoform II (NP_683696.1) and isoform III (NP_683697.1 and NP_683698.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.3-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • FOXP2 polyclonal antibody (Cat # PAB7158) (0.3 ug/mL) staining of human brain (cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • FOXP2 polyclonal antibody (Cat # PAB7158)(2.5 ug/mL) staining of paraffin embedded human prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_055306.1;NP_683696.2;NP_683697.2;NP_683698.2;NP_001166237.1
  • Gene Name:
  • FOXP2
  • Gene Alias:
  • CAGH44,DKFZp686H1726,SPCH1,TNRC10
  • Gene Description:
  • forkhead box P2
  • Gene Summary:
  • This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Multiple alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • CAG repeat protein 44,OTTHUMP00000067772,forkhead/winged-helix transcription factor,speech and language disorder 1,trinucleotide repeat containing 10
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