ICAM5 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ICAM5 polyclonal antibody (Cat # PAB7150) (2.5 ug/mL) staining of paraffin embedded human brain (cerebral cortex). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ICAM5.
Immunogen
A synthetic peptide corresponding to human ICAM5.
Sequence
C-ESPAEGEVFAIQ
Host
Goat
Theoretical MW (kDa)
97.2
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Immunohistochemistry (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ICAM5 polyclonal antibody (Cat # PAB7150) (2.5 ug/mL) staining of paraffin embedded human brain (cerebral cortex). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ICAM5
Entrez GeneID
7087Protein Accession#
NP_0.03250.2Gene Name
ICAM5
Gene Alias
TLCN, TLN
Gene Description
intercellular adhesion molecule 5, telencephalin
Omim ID
601852Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq
Other Designations
intercellular adhesion molecule 5|telencephalin
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Interactome
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Disease
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Publication Reference
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An ICAM-related neuronal glycoprotein, telencephalin, with brain segment-specific expression.
Yoshihara Y, Oka S, Nemoto Y, Watanabe Y, Nagata S, Kagamiyama H, Mori K.
Neuron 1994 Mar; 12(3):541.
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An ICAM-related neuronal glycoprotein, telencephalin, with brain segment-specific expression.
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