HOXB13 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of HOXB13.
Immunogen
A synthetic peptide corresponding to human HOXB13.
Sequence
C-KKVLAKVKNSATP
Host
Goat
Theoretical MW (kDa)
30.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
HOXB13 polyclonal antibody (Cat # PAB7144) (0.1 ug/mL) staining of HeLa cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — HOXB13
Entrez GeneID
10481Protein Accession#
NP_006352.2Gene Name
HOXB13
Gene Alias
PSGD
Gene Description
homeobox B13
Omim ID
604607Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq
Other Designations
homeo box B13
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Interactome
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Disease
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Publication Reference
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Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer.
Zhao Y, Yamashita T, Ishikawa M.
Oncology Reports 2005 Apr; 13(4):721.
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Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer.
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