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Last updated: 2017/1/15
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HCST polyclonal antibody

  • Catalog # : PAB7141
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HCST.
  • Immunogen:
  • A synthetic peptide corresponding to human HCST.
  • Sequence:
  • C-RSPAQEDGKVYIN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 9.5, 9.4
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform 1 (NP_055081.1) but it may recognize isoform 2 lacking residue E81 (NP_001007470.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.2-0.6 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HCST polyclonal antibody (Cat # PAB7141) (0.2 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_055081.1;NP_001007470.1
  • Gene Name:
  • HCST
  • Gene Alias:
  • DAP10,DKFZP586C1522,KAP10,PIK3AP
  • Gene Description:
  • hematopoietic cell signal transducer
  • Gene Summary:
  • This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • DNAX-activation protein 10,kinase assoc pro of ~10kDa,phosphoinositide-3-kinase adaptor protein
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