CYP26B1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CYP26B1 polyclonal antibody (Cat # PAB7139) (4 ug/mL) staining of paraffin embedded human cerebellum. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CYP26B1.
Immunogen
A synthetic peptide corresponding to human CYP26B1.
Sequence
C-SQARSEDKDGRFH
Host
Goat
Theoretical MW (kDa)
57.5
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CYP26B1 polyclonal antibody (Cat # PAB7139) (4 ug/mL) staining of paraffin embedded human cerebellum. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CYP26B1
Entrez GeneID
56603Protein Accession#
NP_063938.1Gene Name
CYP26B1
Gene Alias
CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2
Gene Description
cytochrome P450, family 26, subfamily B, polypeptide 1
Omim ID
605207Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid. [provided by RefSeq
Other Designations
cytochrome P450 retinoid metabolizing protein|cytochrome P450, family 26, subfamily b, polypeptide 1|retinoic acid-metabolizing cytochrome
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Interactome
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Pathway
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Disease
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Publication Reference
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Retinoid signaling determines germ cell fate in mice.
Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, Yashiro K, Chawengsaksophak K, Wilson MJ, Rossant J, Hamada H, Koopman P.
Science 2006 Apr; 312(5773):596.
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Retinoid signaling determines germ cell fate in mice.
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