SLC7A11 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SLC7A11.
Immunogen
A synthetic peptide corresponding to internal region of human SLC7A11.
Sequence
C-KGQTQNFKDAFSGRD
Host
Goat
Theoretical MW (kDa)
55.4
Reactivity
Human, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.02-0.06 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
SLC7A11 polyclonal antibody (Cat # PAB7138) (0.02 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC7A11
Entrez GeneID
23657Protein Accession#
NP_055146.1Gene Name
SLC7A11
Gene Alias
CCBR1, xCT
Gene Description
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
Omim ID
607933Gene Ontology
HyperlinkGene Summary
SLC7A11 is a member of a heteromeric Na(+)-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc(-), the anionic form of cystine is transported in exchange for glutamate.[supplied by OMIM
Other Designations
cystine/glutamate transporter
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Interactome
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Disease
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Publication Reference
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Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT.
Kaleeba JA, Berger EA.
Science 2006 Mar; 311(5769):1921.
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Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT.
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