LHCGR polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of LHCGR.
Immunogen
A synthetic peptide corresponding to human LHCGR.
Sequence
CQGTALLDKTRYTE
Host
Goat
Theoretical MW (kDa)
78.5
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — LHCGR
Entrez GeneID
3973Protein Accession#
NP_000224.2Gene Name
LHCGR
Gene Alias
FLJ41504, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R
Gene Description
luteinizing hormone/choriogonadotropin receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq
Other Designations
luteinising hormone-choriogonadotropin receptor|lutropin/choriogonadotropin receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Multiple luteinizing hormone receptor (LHR) protein variants, interspecies reactivity of anti-LHR mAb clone 3B5, subcellular localization of LHR in human placenta, pelvic floor and brain, and possible role for LHR in the development of abnormal pregnancy, pelvic floor disorders and Alzheimer's disease.
Bukovsky A, Indrapichate K, Fujiwara H, Cekanova M, Ayala ME, Dominguez R, Caudle MR, Wimalsena J, Elder RF, Copas P, Foster JS, Fernando RI, Henley DC, Upadhyaya NB.
Reproductive Biology and Endocrinology 2003 Jun; 1:46.
Application:IHC-Fr, WB-Ti, Human, Pig, Rat, Human brain, pelvic floor, placenta, Pig ovaries, Rat ovaries, uterus.
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Multiple luteinizing hormone receptor (LHR) protein variants, interspecies reactivity of anti-LHR mAb clone 3B5, subcellular localization of LHR in human placenta, pelvic floor and brain, and possible role for LHR in the development of abnormal pregnancy, pelvic floor disorders and Alzheimer's disease.
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