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Last updated: 2017/6/25
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AGTR1 polyclonal antibody

  • Catalog # : PAB7122
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of AGTR1.
  • Immunogen:
  • A synthetic peptide corresponding to human AGTR1.
  • Sequence:
  • C-EIQKNKPRNDDIFK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 41.1
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • AGTR1 polyclonal antibody (Cat # PAB7122) (0.3 ug/mL) staining of mouse liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 185
  • Protein Accession#:
  • NP_000676.1;NP_004826.2;NP_033611.1;NP_114038.1;NP_114438.1
  • Gene Name:
  • AGTR1
  • Gene Alias:
  • AG2S,AGTR1A,AGTR1B,AT1,AT1B,AT1R,AT2R1,AT2R1A,AT2R1B,HAT1R
  • Gene Description:
  • angiotensin II receptor, type 1
  • Gene Summary:
  • Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq
  • Other Designations:
  • angiotensin receptor 1,angiotensin receptor 1B,type-1B angiotensin II receptor
  • Related Disease
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