ALOX5AP polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ALOX5AP.
Immunogen
A synthetic peptide corresponding to internal region of human ALOX5AP.
Sequence
C-HKVEHESRTQNGR
Host
Goat
Theoretical MW (kDa)
18.2
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
ALOX5AP polyclonal antibody (Cat # PAB7117) (0.1 ug/mL) staining of human U-937 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ALOX5AP polyclonal antibody (Cat # PAB7117)(3.8 ug/mL) staining of paraffin embedded human spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — ALOX5AP
Entrez GeneID
241Protein Accession#
NP_001620.2Gene Name
ALOX5AP
Gene Alias
FLAP
Gene Description
arachidonate 5-lipoxygenase-activating protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq
Other Designations
MK-886-binding protein|OTTHUMP00000018204|five-lipoxygenase activating protein
-
Interactome
-
Disease
-
Publication Reference
-
ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance.
Kaaman M, Rydén M, Axelsson T, Nordström E, Sicard A, Bouloumié A, Langin D, Arner P, Dahlman I.
International Journal of Obesity 2006 Mar; 30(3):447.
-
ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com