FBXL3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
FBXL3 polyclonal antibody (Cat # PAB7099) (1 ug/mL) staining of human adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FBXL3.
Immunogen
A synthetic peptide corresponding to human FBXL3.
Sequence
KRGGRDSDRNSSEE-C
Host
Goat
Theoretical MW (kDa)
48.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FBXL3 polyclonal antibody (Cat # PAB7099) (1 ug/mL) staining of human adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FBXL3
Entrez GeneID
26224Protein Accession#
NP_0.36290.1Gene Name
FBXL3
Gene Alias
FBL3, FBL3A, FBXL3A
Gene Description
F-box and leucine-rich repeat protein 3
Omim ID
605653Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq
Other Designations
F-box and leucine-rich repeat protein 3A|F-box protein Fbl3a|OTTHUMP00000018519
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Interactome
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Publication Reference
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Fibulins 3 and 5 antagonize tumor angiogenesis in vivo.
Albig AR, Neil JR, Schiemann WP.
Cancer Research 2006 Mar; 66(5):2621.
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Fibulins 3 and 5 antagonize tumor angiogenesis in vivo.
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