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Last updated: 2017/9/17
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TSPO polyclonal antibody

  • Catalog # : PAB7095
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TSPO.
  • Immunogen:
  • A synthetic peptide corresponding to human TSPO.
  • Sequence:
  • C-RDNHGWRGGRRLPE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 18.8
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize one isoform (NP_000705.2) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.1-0.3 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TSPO polyclonal antibody (Cat # PAB7095) (0.1 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • TSPO polyclonal antibody (Cat # PAB7095) (2.5 ug/mL) staining of paraffin embedded human colon. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 706
  • Gene Name:
  • TSPO
  • Gene Alias:
  • BZRP,DBI,IBP,MBR,PBR,PKBS,PTBR,mDRC,pk18
  • Gene Description:
  • translocator protein (18kDa)
  • Gene Summary:
  • Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028891,benzodiazepine peripheral binding site,mitochondrial benzodiazepine receptor,peripheral benzodiazepine receptor,peripheral-type benzodiazepine receptor,translocator protein
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