VPS29 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of VPS29.
Immunogen
A synthetic peptide corresponding to human VPS29.
Sequence
CTGNLCTKESYDYLK
Host
Goat
Theoretical MW (kDa)
20.5, 20.9
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_057310.1 and NP_476528.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — VPS29
Entrez GeneID
51699Protein Accession#
NP_057310.1;NP_476528.1Gene Name
VPS29
Gene Alias
DC15, DC7, DKFZp564F0223, FLJ20492, PEP11
Gene Description
vacuolar protein sorting 29 homolog (S. cerevisiae)
Omim ID
606932Gene Ontology
HyperlinkGene Summary
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene. [provided by RefSeq
Other Designations
retromer protein|vacuolar protein sorting 29|vacuolar sorting protein VPS29/PEP11|x 007 protein
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Interactome
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Publication Reference
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A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica.
Nakada-Tsukui K, Saito-Nakano Y, Ali V, Nozaki T.
Molecular Biology of the Cell 2005 Nov; 16(11):5294.
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A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica.
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