FXR1 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
FXR1 polyclonal antibody (Cat # PAB7080) (0.2 ug/mL) staining of NIH/3T3 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FXR1.
Immunogen
A synthetic peptide corresponding to human FXR1.
Sequence
C-RIEGDNENKLPRED
Host
Goat
Theoretical MW (kDa)
69.7, 60.8, 59.9
Reactivity
Mouse
Specificity
This antibody is expected to recognize all reported isoforms (NP_005078.2, NP_001013456.1 and NP_001013457.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
FXR1 polyclonal antibody (Cat # PAB7080) (0.2 ug/mL) staining of NIH/3T3 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FXR1
Entrez GeneID
8087Protein Accession#
NP_005078.2;NP_001013456.1;NP_001013457.1Gene Name
FXR1
Gene Alias
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Gene Description
fragile X mental retardation, autosomal homolog 1
Omim ID
600819Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
fragile X mental retardation-related protein 1
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Interactome
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Publication Reference
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Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree.
Coon H, Matsunami N, Stevens J, Miller J, Pingree C, Camp NJ, Thomas A, Krasny L, Lainhart J, Leppert MF, McMahon W.
Human Heredity 2005 Jan; 60(4):220.
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Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree.
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