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Last updated: 2017/3/19
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DISC1 polyclonal antibody

  • Catalog # : PAB7079
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of DISC1.
  • Immunogen:
  • A synthetic peptide corresponding to human DISC1.
  • Sequence:
  • C-HSEDKRKTPLKVLE
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 93.6, 91.1
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoforms L ( NP_061132.2) and Lv (NP_001012975.1) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • DISC1 polyclonal antibody (Cat # PAB7079) (0.1 ug/mL) staining of human brain (hippocampus) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_001012975.1;NP_061132.2
  • Gene Name:
  • DISC1
  • Gene Alias:
  • C1orf136,FLJ13381,FLJ21640,FLJ25311,FLJ41105,KIAA0457,SCZD9
  • Gene Description:
  • disrupted in schizophrenia 1
  • Gene Summary:
  • This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035959,OTTHUMP00000035960
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