PRDX2 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
PRDX2 polyclonal antibody (Cat # PAB7050) (1 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PRDX2.
Immunogen
A synthetic peptide corresponding to human PRDX2.
Sequence
C-NVDDSKEYFSKHN
Host
Goat
Theoretical MW (kDa)
21.9, 16.0
Reactivity
Human, Mouse
Specificity
This antibody is expected to recognize isoforms a and b only (NP_00580.03 and NP_859427.1 respectively).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PRDX2 polyclonal antibody (Cat # PAB7050) (1 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PRDX2
Entrez GeneID
7001Protein Accession#
NP_00580.03;NP_859427.1Gene Name
PRDX2
Gene Alias
MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA
Gene Description
peroxiredoxin 2
Omim ID
600538Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
natural killer-enhancing factor B|thiol-specific antioxidant 1|thioredoxin peroxidase 1|thioredoxin-dependent peroxide reductase 1|torin
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Interactome
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Disease
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Publication Reference
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Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models.
Kato S, Kato M, Abe Y, Matsumura T, Nishino T, Aoki M, Itoyama Y, Asayama K, Awaya A, Hirano A, Ohama E.
Acta Neuropathologica 2005 Aug; 110(2):101.
Application：IHC-P, WB-Ti, Human, Spinal cord cervical segments from patients with amyotrophic lateral sclerosis.
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Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models.
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