FOSL1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FOSL1.
Immunogen
A synthetic peptide corresponding to human FOSL1.
Sequence
C-QREIEELQKQKER
Host
Goat
Theoretical MW (kDa)
29.4
Reactivity
Human
Specificity
This antibody is not expected to cross-react with V-FOS.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FOSL1 polyclonal antibody (Cat # PAB7046) (1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FOSL1
Entrez GeneID
8061Protein Accession#
NP_005429.1Gene Name
FOSL1
Gene Alias
FRA, FRA1, fra-1
Gene Description
FOS-like antigen 1
Omim ID
136515Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq
Other Designations
FOS-like antigen-1|Fos-related antigen
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Interactome
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Pathway
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Disease
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Publication Reference
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FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells.
Belguise K, Kersual N, Galtier F, Chalbos D.
Oncogene 2005 Feb; 24(8):1434.
Application:WB-Ce, WB-Tr, Human, MCF-7, T47D, ZR75.1, BT474, SKBR3, MDA436MDA435, MDA231 cells.
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FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells.
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